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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
18.18
Human Site:
Y144
Identified Species:
28.57
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
Y144
C
N
I
G
V
P
W
Y
D
R
E
A
N
D
A
Chimpanzee
Pan troglodytes
XP_520790
703
80912
V140
D
L
W
E
A
C
S
V
G
I
P
Y
H
D
R
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
Y144
C
N
I
G
V
P
W
Y
D
R
E
A
N
D
A
Dog
Lupus familis
XP_534869
703
80957
V140
D
L
W
E
A
C
S
V
G
I
P
Y
H
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
Y144
C
N
I
G
V
P
W
Y
D
R
E
A
N
D
A
Rat
Rattus norvegicus
A2RRU1
738
84053
Y144
C
N
I
G
V
P
W
Y
D
R
E
A
N
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
Y144
C
S
I
G
V
P
W
Y
D
R
E
A
N
D
A
Chicken
Gallus gallus
XP_416432
704
81032
I140
E
F
W
D
A
T
N
I
G
I
P
F
H
D
R
Frog
Xenopus laevis
NP_001084863
702
80811
V140
E
F
W
D
C
C
T
V
G
I
P
Y
N
D
R
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
I139
E
L
W
E
K
C
N
I
G
V
P
W
F
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
I124
L
R
S
R
G
Y
K
I
H
T
G
R
W
L
V
Honey Bee
Apis mellifera
XP_624707
692
79590
F125
G
N
P
Q
I
I
L
F
D
I
G
S
A
A
W
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
Q112
R
A
A
M
K
R
F
Q
A
D
G
F
R
C
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
H133
V
G
I
P
S
P
E
H
D
H
E
T
N
D
A
Red Bread Mold
Neurospora crassa
O93869
706
80888
N131
A
S
I
P
S
P
D
N
D
E
E
T
N
E
A
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
93.3
6.6
13.3
6.6
N.A.
0
13.3
0
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
N.A.
100
13.3
13.3
6.6
N.A.
0
33.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
20
0
0
0
7
0
0
34
7
7
47
% A
% Cys:
34
0
0
0
7
27
0
0
0
0
0
0
0
7
0
% C
% Asp:
14
0
0
14
0
0
7
0
54
7
0
0
0
74
0
% D
% Glu:
20
0
0
20
0
0
7
0
0
7
47
0
0
7
0
% E
% Phe:
0
14
0
0
0
0
7
7
0
0
0
14
7
0
0
% F
% Gly:
7
7
0
34
7
0
0
0
34
0
20
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
7
0
0
20
0
0
% H
% Ile:
0
0
47
0
7
7
0
20
0
34
0
0
0
0
0
% I
% Lys:
0
0
0
0
14
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
7
20
0
0
0
0
7
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
34
0
0
0
0
14
7
0
0
0
0
54
0
0
% N
% Pro:
0
0
7
14
0
47
0
0
0
0
34
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
7
0
7
0
7
0
0
0
34
0
7
7
0
34
% R
% Ser:
0
14
7
0
14
0
14
0
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
7
7
0
0
7
0
14
0
0
0
% T
% Val:
7
0
0
0
34
0
0
20
0
7
0
0
0
0
7
% V
% Trp:
0
0
34
0
0
0
34
0
0
0
0
7
7
0
7
% W
% Tyr:
0
0
0
0
0
7
0
34
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _